One of the more debated topics in the urology arena over the years includes the relationship between testosterone and prostate cancer. Many men are curious about whether or not testosterone could be putting them at higher risk for developing prostate cancer. They want to know if men can go back on testosterone therapy after being treated for prostate cancer and how manipulating your testosterone level can be used in the management of more advanced prostate cancer cases. Stay tuned for more!

Today, we have an international prostate cancer expert, Dr. Judd Moul, from Duke University, making a second appearance on the podcast. Dr. Moul helped us kick off the initial launch of the podcast as the guest for episode two, one of our most popular episodes to date, covering prostate-specific antigen, a man’s check engine light. For our listeners who have not yet met Dr. Moul, he is an expert when it comes to prostate cancer. He joined the Duke University faculty in 2004, after a career in the US Army Medical Corps, mainly at Walter Reed Army Medical Center. He is a retired Colonel and noted researcher and clinician in the area of prostate cancer. He has authored and co-authored more than 275 scientific manuscripts and book chapters. He served as the editor for Prostate Cancer and Prostatic Disease Journal and is a popular speaker and lecturer, having been a visiting professor and keynote speaker throughout the US and the world. Be sure to listen in to find out all you need to know about testosterone and prostate cancer.

Disclaimer: The Prostate Health Podcast is for informational purposes only. Nothing in this podcast should be construed as medical advice. By listening to the podcast, no physician-patient relationship has been formed. For more information and counseling, you must contact your personal physician or urologist with questions about your unique situation.

Show highlights:

  • Dr. Moul explains when we first became aware of any relationship between testosterone and prostate cancer.
  • Dr. Moul explains how treatment has evolved in manipulating the hormone levels for men with advanced prostate cancer and how the treatment works in reducing the testosterone level.
  • Dr. Moul describes which men with prostate cancer are candidates for androgen deprivation or hormonal therapy.
  • The testosterone level that doctors are shooting for, for the men who are being treated with hormonal therapy.
  • Some of the potential side-effects that men need to be aware of when they are on hormonal therapy.
  • Dr. Moul talks about whether or not prostate cancer can ultimately become resistant to testosterone suppression.
  • The available options for those men who start having a rising PSA or start showing signs of resistance to the therapy.
  • Dr. Moul explains if men need to remain on their hormone therapy.
  • Dr. Moul discusses whether men with no prior history of prostate cancer should be concerned that taking testosterone supplementation could put them at higher risk of developing prostate cancer.
  • Dr. Moul talks about where we stand currently in terms of when it might be safe to go ahead and restart testosterone supplementation following definitive treatment for prostate cancer.

Links and resources:

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Dr. Judd Moul’s website